Pemiscot County is available for adoption.
If you have a local connection to Pemiscot County or an interest in Missouri in general,
Please consider joining the MOGenWeb as a County Coordinator.
Requirements are simple, peruse them here.
https://mogenweb.org/moccguide.htm
MOGenWeb Policies and Procedures
https://www.mogenweb.org/pol-pro.htm
Contact the State Coordinator if you are interested.
In addition:, we would appreciate any contribution that you would like to make to this
site: biographies, obituaries, birth, marriage, death info, grave info, photographs....etc
Pemiscot
County, Missouri
Pemiscot County lies in Missouri’s Bootheel region, a fertile Mississippi River delta shaped by early Indigenous presence, French colonial activity, and later American settlement. The area’s rich alluvial soil drew farmers and traders throughout the early 19th century, and river landings along the Mississippi became important points of travel, commerce, and migration.
Pemiscot County was organized on February 19, 1851, carved from the older New Madrid County during a period of rapid development in southeast Missouri. When officials met to establish county government, Caruthersville was selected as the county seat, chosen for its strategic riverfront location and its emergence as a reliable center for trade, courts, and civic life.
Throughout the late 1800s and early 1900s, Pemiscot County grew through agriculture — especially cotton — as well as river commerce, levee construction, and the development of small towns across the delta. These communities produced extensive courthouse records, church registers, cemetery histories, and land transactions that document generations of families who lived along Missouri’s southernmost river country.
For genealogists, Pemiscot County offers strong research opportunities: early land and probate records, long‑running courthouse archives, river‑town histories, and family lines tied to both agricultural settlements and Mississippi River trade routes.